Dezheng Huo

Research Summary
Dr. Huo’s research interests focus on the genetic, molecular, and environmental factors underlying etiology, prognosis, and treatment of cancers, particularly as they relate to cancer in underserved populations. His research spans across several areas of cancer epidemiology and clinical epidemiology, including: 1. Genetic epidemiology of breast cancer, particular in women of African ancestry with the use of genome-wide association and whole genome sequencing approach. 2. Environmental and lifestyle factors for breast cancer etiology in African women and risk prediction model building, and strategy for cancer screening. 3. Health disparity in breast cancer outcomes in multiethnic patient cohort study with multi-dimensional data. 4. Investigation of the utilization and effectiveness of cancer treatment in real world using Big data. 5. Prenatal exposure to diethylstilbestrol and clear cell adenocarcinoma of vagina and cervix, as well as other health conditions in later life. 6. Epigenetics and non-coding RNAs, such as microRNAs in relationship to cancer prognosis and survival.
Breast Cancer, Genetics, Population, Genetic Epidemiology, Health Disparity, Outcomes Research, Risk Prediction
Biosciences Graduate Program Association
Awards & Honors
  • 2000 - Student Travel Award University of Illinois at Chicago
  • 2005 - Delta Omega National Honor Society in Public Health
  • 2005 - Haenszel Award for Excellence in Research University of Illinois at Chicago
  • 2008 - Breast Cancer Research Program study section U.S. Army Medical Research and Materiel Command
  • 2010 - Breast Cancer Research Program study section U.S. Army Medical Research and Materiel Command
  • 2013 - 2014 Breast Cancer Research Program study section U.S. Army Medical Research and Materiel Command
  • 2014 - Distinguished Investigator Junior Award University of Chicago
  • 2015 - Study section of U54 NIH/NIMHD
  • 2016 - Runner-up in the Up For A Challenge – Stimulating Innovation in Breast Cancer Genetic Epidemiology National Cancer Institute
  • 2017 - Study section of P01 NIH/NCI
  • 2017 - Study section of U01, H3Africa NIH/NHGRI
  • 2018 - 2023 Study section of R01/R21 NIH/NCI
  • 2019 - Study section of P01 NIH/NCI
  1. Cancer Genetic Services in a Low- to Middle-Income Country: Cross-Sectional Survey Assessing Willingness to Undergo and Pay for Germline Genetic Testing. JCO Glob Oncol. 2023 02; 9:e2100140. View in: PubMed

  2. A metabolome-wide case-control study of african american breast cancer patients. BMC Cancer. 2023 Feb 23; 23(1):183. View in: PubMed

  3. Clinicopathologic Characteristics and Prognosis of ERBB2-Low Breast Cancer Among Patients in the National Cancer Database. JAMA Oncol. 2023 Feb 23. View in: PubMed

  4. The optimization of postoperative radiotherapy in de novo stage IV breast cancer: evidence from real-world data to personalize treatment decisions. Sci Rep. 2023 Feb 18; 13(1):2880. View in: PubMed

  5. Electronic Health Record-Based Absolute Risk Prediction Model for Esophageal Cancer in the Chinese Population: Model Development and External Validation. JMIR Public Health Surveill. 2023 Mar 15; 9:e43725. View in: PubMed

  6. Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry. Genome Med. 2023 01 26; 15(1):7. View in: PubMed

  7. Factors associated with breast disorders detected by clinical breast examination during pregnancy and six months postpartum in Ibadan, South-western Nigeria. J Public Health Afr. 2022 Sep 07; 13(3):1812. View in: PubMed

  8. Validation of the Nigerian Breast Cancer Study Model for Predicting Individual Breast Cancer Risk in Cameroon and Uganda. Cancer Epidemiol Biomarkers Prev. 2023 01 09; 32(1):98-104. View in: PubMed

  9. An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancer. Hum Mol Genet. 2023 01 01; 32(1):139-150. View in: PubMed

  10. Oncology Training Needs Assessment Among Health Care Professionals in Nigeria. JCO Glob Oncol. 2022 05; 8:e2200017. View in: PubMed

  11. Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Hum Mol Genet. 2022 09 10; 31(18):3133-3143. View in: PubMed

  12. Differences in somatic TP53 mutation type in breast tumors by race and receptor status. Breast Cancer Res Treat. 2022 Apr; 192(3):639-648. View in: PubMed

  13. Assessment of Breast Cancer Management in Sub-Saharan Africa. JCO Glob Oncol. 2021 09; 7:1593-1601. View in: PubMed

  14. Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes. Nat Commun. 2021 11 26; 12(1):6946. View in: PubMed

  15. Associations between age of menarche and genetic variation in women of African descent: genome-wide association study and polygenic score analysis. J Epidemiol Community Health. 2022 04; 76(4):411-417. View in: PubMed

  16. Hypofractionated Radiation Therapy for Breast Cancer: Financial Risk and Expenditures in the United States, 2008 to 2017. Int J Radiat Oncol Biol Phys. 2022 03 01; 112(3):654-662. View in: PubMed

  17. The impact of coronavirus disease 2019 on the quality of life and treatment disruption of patients with breast cancer in a multiethnic cohort. Cancer. 2021 11 01; 127(21):4072-4080. View in: PubMed

  18. The impact of site-specific digital histology signatures on deep learning model accuracy and bias. Nat Commun. 2021 07 20; 12(1):4423. View in: PubMed

  19. Prenatal Diethylstilbestrol Exposure and Cancer Risk in Males. Cancer Epidemiol Biomarkers Prev. 2021 10; 30(10):1826-1833. View in: PubMed

  20. Has Hypofractionated Whole-Breast Radiation Therapy Become the Standard of Care in the United States? An Updated Report from National Cancer Database. Clin Breast Cancer. 2022 01; 22(1):e8-e20. View in: PubMed

  21. Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women. Nat Commun. 2021 07 07; 12(1):4198. View in: PubMed

  22. Instrumental variable approach for estimating a causal hazard ratio: application to the effect of postmastectomy radiotherapy on breast cancer patients. Obs Stud. 2019; 5:141-162. View in: PubMed

  23. Development and external validation of a breast cancer absolute risk prediction model in Chinese population. Breast Cancer Res. 2021 05 29; 23(1):62. View in: PubMed

  24. Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. J Natl Cancer Inst. 2021 09 04; 113(9):1168-1176. View in: PubMed

  25. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. Am J Hum Genet. 2021 04 01; 108(4):564-582. View in: PubMed

  26. Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients. Breast Cancer Res. 2021 02 04; 23(1):18. View in: PubMed

  27. Prenatal diethylstilbestrol exposure and risk of diabetes, gallbladder disease, and pancreatic disorders and malignancies. J Dev Orig Health Dis. 2021 08; 12(4):619-626. View in: PubMed

  28. Racial disparities in survival outcomes among breast cancer patients by molecular subtypes. Breast Cancer Res Treat. 2021 Feb; 185(3):841-849. View in: PubMed

  29. Circulating Insulin-Like Growth Factor-1 and Risk of Total and 19 Site-Specific Cancers: Cohort Study Analyses from the UK Biobank. Cancer Epidemiol Biomarkers Prev. 2020 11; 29(11):2332-2342. View in: PubMed

  30. Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Sci Rep. 2020 06 16; 10(1):9688. View in: PubMed

  31. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. BJU Int. 2020 07; 126(1):14-25. View in: PubMed

  32. Propensity score analysis of the prognostic value of genomic assays for breast cancer in diverse populations using the National Cancer Data Base. Cancer. 2020 09 01; 126(17):4013-4022. View in: PubMed

  33. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Eur Urol. 2020 07; 78(1):97-109. View in: PubMed

  34. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. Urology. 2020 08; 142:1-13. View in: PubMed

  35. Guidelines for Reporting of Figures and Tables for Clinical Research in Urology. J Urol. 2020 07; 204(1):121-133. View in: PubMed

  36. Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015. Breast Cancer Res Treat. 2020 Jun; 181(3):623-633. View in: PubMed

  37. Traditional medicine usage among adult women in Ibadan, Nigeria: a cross-sectional study. BMC Complement Med Ther. 2020 Mar 20; 20(1):93. View in: PubMed

  38. Gender Identity and Sexual Orientation Identity in Women and Men Prenatally Exposed to Diethylstilbestrol. Arch Sex Behav. 2020 02; 49(2):447-454. View in: PubMed

  39. Prevalence of Inherited Mutations in Breast Cancer Predisposition Genes among Women in Uganda and Cameroon. Cancer Epidemiol Biomarkers Prev. 2020 02; 29(2):359-367. View in: PubMed

  40. Soy intake and breast cancer risk: a prospective study of 300,000 Chinese women and a dose-response meta-analysis. Eur J Epidemiol. 2020 Jun; 35(6):567-578. View in: PubMed

  41. Two truncating variants in FANCC and breast cancer risk. Sci Rep. 2019 08 29; 9(1):12524. View in: PubMed

  42. Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study. Cancer Med. 2019 09; 8(12):5609-5618. View in: PubMed

  43. Prenatal Diethylstilbestrol Exposure and Risk of Depression in Women and Men. Epidemiology. 2019 09; 30(5):679-686. View in: PubMed

  44. Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers. Br J Cancer. 2019 07; 121(2):180-192. View in: PubMed

  45. Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria. Int J Cancer. 2019 12 15; 145(12):3321-3333. View in: PubMed

  46. BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry. Hum Mutat. 2019 10; 40(10):1781-1796. View in: PubMed

  47. Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk. Int J Epidemiol. 2019 10 01; 48(5):1727-1730. View in: PubMed

  48. The association between weight at birth and breast cancer risk revisited using Mendelian randomisation. Eur J Epidemiol. 2019 Jun; 34(6):591-600. View in: PubMed

  49. Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features. Nat Commun. 2019 01 14; 10(1):288. View in: PubMed

  50. Identification of novel common breast cancer risk variants at the 6q25 locus?among Latinas. Breast Cancer Res. 2019 01 14; 21(1):3. View in: PubMed

  51. Guidelines for Reporting of Statistics for Clinical Research in Urology. J Urol. 2019 03; 201(3):595-604. View in: PubMed

  52. Reproductive and hormone-related outcomes in women whose mothers were exposed in utero to diethylstilbestrol (DES): A report from the US National Cancer Institute DES Third Generation Study. Reprod Toxicol. 2019 03; 84:32-38. View in: PubMed

  53. Guidelines for Reporting of Statistics for Clinical Research in Urology. Eur Urol. 2019 03; 75(3):358-367. View in: PubMed

  54. Guidelines for reporting of statistics for clinical research in urology. BJU Int. 2019 03; 123(3):401-410. View in: PubMed

  55. Community clinical practice patterns and mortality in patients with intermediate oncotype DX recurrence scores: Who benefits from chemotherapy? Cancer. 2019 01 15; 125(2):213-222. View in: PubMed

  56. Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features. Nat Commun. 2018 10 16; 9(1):4181. View in: PubMed

  57. Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study. J Natl Cancer Inst. 2019 04 01; 111(4):350-364. View in: PubMed

  58. A longitudinal study of the prevalence and characteristics of breast disorders detected by clinical breast examination during pregnancy and six months postpartum in Ibadan, Southwestern Nigeria. BMC Womens Health. 2018 09 19; 18(1):152. View in: PubMed

  59. Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers. Clin Cancer Res. 2019 03 15; 25(6):1786-1794. View in: PubMed

  60. Inherited Breast Cancer in Nigerian Women. J Clin Oncol. 2018 10 01; 36(28):2820-2825. View in: PubMed

  61. Frequency of Germline Mutations in Cancer Susceptibility Genes in Malignant Mesothelioma. J Clin Oncol. 2018 10 01; 36(28):2863-2871. View in: PubMed

  62. Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer. Cancer Epidemiol Biomarkers Prev. 2018 09; 27(9):1057-1064. View in: PubMed

  63. Genetic variation in the Hippo pathway and breast cancer risk in women of African ancestry. Mol Carcinog. 2018 10; 57(10):1311-1318. View in: PubMed

  64. Follow-up of Patients with Clear-Cell Adenocarcinoma of the Vagina and Cervix. N Engl J Med. 2018 05 03; 378(18):1746-1748. View in: PubMed

  65. Development of a Breast Cancer Risk Prediction Model for Women in Nigeria. Cancer Epidemiol Biomarkers Prev. 2018 06; 27(6):636-643. View in: PubMed

  66. Reported Biologic Differences in Breast Cancer by Race Due to Disparities in Screening-Reply. JAMA Oncol. 2018 06 01; 4(6):883-884. View in: PubMed

  67. Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations. Hum Mutat. 2018 05; 39(5):593-620. View in: PubMed

  68. A meta-analysis approach with filtering for identifying gene-level gene-environment interactions. Genet Epidemiol. 2018 07; 42(5):434-446. View in: PubMed

  69. Assessment of peri-polyp biopsy specimens of flat mucosa in patients with inflammatory bowel disease. Gastrointest Endosc. 2018 May; 87(5):1304-1309. View in: PubMed

  70. Genetic variants demonstrating flip-flop phenomenon and breast cancer risk prediction among women of African ancestry. Breast Cancer Res Treat. 2018 Apr; 168(3):703-712. View in: PubMed

  71. De novo metastasis in breast cancer: occurrence and overall survival stratified by molecular subtype. Clin Exp Metastasis. 2017 12; 34(8):457-465. View in: PubMed

  72. Association of Pancreatic Cancer Susceptibility Variants with Risk of Breast Cancer in Women of European and African Ancestry. Cancer Epidemiol Biomarkers Prev. 2018 01; 27(1):116-118. View in: PubMed

  73. Racial disparities in omission of oncotype DX but no racial disparities in chemotherapy receipt following completed oncotype DX test results. Breast Cancer Res Treat. 2018 Feb; 168(1):207-220. View in: PubMed

  74. Prenatal diethylstilbestrol exposure and cancer risk in women. Environ Mol Mutagen. 2019 06; 60(5):395-403. View in: PubMed

  75. A Prospective Cohort Study of Prenatal Diethylstilbestrol Exposure and Cardiovascular Disease Risk. J Clin Endocrinol Metab. 2018 01 01; 103(1):206-212. View in: PubMed

  76. Trans-ethnic predicted expression genome-wide association analysis identifies a gene for estrogen receptor-negative breast cancer. PLoS Genet. 2017 Sep; 13(9):e1006727. View in: PubMed

  77. Genetic variation in the vitamin D related pathway and breast cancer risk in women of African ancestry in the root consortium. Int J Cancer. 2018 01 01; 142(1):36-43. View in: PubMed

  78. Pilot Survey of Breast Cancer Management in Sub-Saharan Africa. J Glob Oncol. 2017 Jun; 3(3):194-200. View in: PubMed

  79. Incidence rates and risks of diethylstilbestrol-related clear-cell adenocarcinoma of the vagina and cervix: Update after 40-year follow-up. Gynecol Oncol. 2017 09; 146(3):566-571. View in: PubMed

  80. A functionally significant SNP in TP53 and breast cancer risk in African-American women. NPJ Breast Cancer. 2017; 3:5. View in: PubMed

  81. Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium. Carcinogenesis. 2017 08 01; 38(8):789-796. View in: PubMed

  82. Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction. Breast Cancer Res Treat. 2017 Aug; 164(3):707-717. View in: PubMed

  83. A Tale of Two Cancers: Traveling to Treat Pancreatic and Thyroid Cancer. J Am Coll Surg. 2017 Jul; 225(1):125-136.e6. View in: PubMed

  84. Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas. JAMA Oncol. 2017 12 01; 3(12):1654-1662. View in: PubMed

  85. Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores. J Clin Oncol. 2017 Jul 10; 35(20):2240-2250. View in: PubMed

  86. Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry. Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1016-1026. View in: PubMed

  87. Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Hum Mol Genet. 2016 11 01; 25(21):4835-4846. View in: PubMed

  88. Evaluation of the Quality of Adjuvant Endocrine Therapy Delivery for Breast Cancer Care in the United States. JAMA Oncol. 2017 Jul 01; 3(7):928-935. View in: PubMed

  89. Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States. Breast Cancer Res Treat. 2017 04; 162(2):317-328. View in: PubMed

  90. Household biomass fuel use, asthma symptoms severity, and asthma underdiagnosis in rural schoolchildren in Nigeria: a cross-sectional observational study. BMC Pulm Med. 2017 01 05; 17(1):3. View in: PubMed

  91. Sorafenib (SOR) in patients (pts) with advanced/recurrent uterine carcinoma (UCA) or carcinosarcoma (CS): A phase II trial of the University of Chicago, PMH, and California Phase II Consortia. J Clin Oncol. 2008 May 20; 26(15_suppl):5585. View in: PubMed

  92. Genetic and Epigenetic Regulation of TOX3 Expression in Breast Cancer. PLoS One. 2016; 11(11):e0165559. View in: PubMed

  93. Effect of BRCA germline mutations on breast cancer prognosis: A systematic review and meta-analysis. Medicine (Baltimore). 2016 Oct; 95(40):e4975. View in: PubMed

  94. Biomass fuel exposure and asthma symptoms among rural school children in Nigeria. J Asthma. 2017 May; 54(4):347-356. View in: PubMed

  95. miR-206 Inhibits Stemness and Metastasis of Breast Cancer by Targeting MKL1/IL11 Pathway. Clin Cancer Res. 2017 Feb 15; 23(4):1091-1103. View in: PubMed

  96. Identification of a circulating microRNA signature to distinguish recurrence in breast cancer patients. Oncotarget. 2016 08 23; 7(34):55231-55248. View in: PubMed

  97. Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry. Hum Genet. 2016 10; 135(10):1145-59. View in: PubMed

  98. Bayesian adjustment for the misclassification in both dependent and independent variables with application to a breast cancer study. Stat Med. 2016 10 15; 35(23):4252-63. View in: PubMed

  99. The Molecular Chaperone GRP78 Contributes to Toll-like Receptor 3-mediated Innate Immune Response to Hepatitis C Virus in Hepatocytes. J Biol Chem. 2016 Jun 03; 291(23):12294-309. View in: PubMed

  100. Genetic anticipation in BRCA1/BRCA2 families after controlling for ascertainment bias and cohort effect. Cancer. 2016 06 15; 122(12):1913-20. View in: PubMed

  101. Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. Cancer. 2016 Jan 15; 122(2):304-11. View in: PubMed

  102. Increased utilization of postmastectomy radiotherapy in the United States from 2003 to 2011 in patients with one to three tumor positive nodes. J Surg Oncol. 2015 Dec; 112(8):809-14. View in: PubMed

  103. National Prostate Cancer Screening Rates After the 2012 US Preventive Services Task Force Recommendation Discouraging Prostate-Specific Antigen-Based Screening. J Clin Oncol. 2015 Aug 01; 33(22):2416-23. View in: PubMed

  104. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. JAMA. 2015 Apr 07; 313(13):1347-61. View in: PubMed

  105. Prevention of colorectal cancer and dietary management. Chin Clin Oncol. 2013 Jun; 2(2):13. View in: PubMed

  106. Use of Postmastectomy Radiotherapy and Survival Rates for Breast Cancer Patients with T1-T2 and One to Three Positive Lymph Nodes. Ann Surg Oncol. 2015 Dec; 22(13):4295-304. View in: PubMed

  107. Breast cancer risk after full-term pregnancies among African women from Nigeria, Cameroon, and Uganda. Cancer. 2015 Jul 01; 121(13):2237-43. View in: PubMed

  108. A randomized trial comparing standard outcomes in two treatment models for substance users with tuberculosis. Int J Tuberc Lung Dis. 2015 Mar; 19(3):326-32. View in: PubMed

  109. ?-catenin regulates c-Myc and CDKN1A expression in breast cancer cells. Mol Carcinog. 2016 May; 55(5):431-9. View in: PubMed

  110. The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon. Gut. 2016 Mar; 65(3):456-64. View in: PubMed

  111. Heterogeneity in hormone-receptor status and survival outcomes among women with synchronous and metachronous bilateral breast cancers. Breast. 2015 Apr; 24(2):131-6. View in: PubMed

  112. Inherited predisposition to breast cancer among African American women. Breast Cancer Res Treat. 2015 Jan; 149(1):31-9. View in: PubMed

  113. An epidemiologic investigation of physical activity and breast cancer risk in Africa. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2748-56. View in: PubMed

  114. The role of statins for primary prevention in non-elderly colorectal cancer patients. Anticancer Res. 2014 Sep; 34(9):5043-50. View in: PubMed

  115. Alcohol consumption and breast cancer risk among women in three sub-Saharan African countries. PLoS One. 2014; 9(9):e106908. View in: PubMed

  116. A comprehensive examination of breast cancer risk loci in African American women. Hum Mol Genet. 2014 Oct 15; 23(20):5518-26. View in: PubMed

  117. Discordance in hormone receptor status among primary, metastatic, and second primary breast cancers: biological difference or misclassification? Oncologist. 2014 Jun; 19(6):592-601. View in: PubMed

  118. Utilization of accelerated partial breast irradiation for ductal carcinoma in situ, 2003-2011: report from the national cancer database. Ann Surg Oncol. 2014 Oct; 21(11):3457-65. View in: PubMed

  119. Pilot study demonstrating potential association between breast cancer image-based risk phenotypes and genomic biomarkers. Med Phys. 2014 Mar; 41(3):031917. View in: PubMed

  120. National trends in prostate cancer screening among older American men with limited 9-year life expectancies: evidence of an increased need for shared decision making. Cancer. 2014 May 15; 120(10):1491-8. View in: PubMed

  121. Contralateral prophylactic mastectomy and survival: report from the National Cancer Data Base, 1998-2002. Breast Cancer Res Treat. 2013 Dec; 142(3):465-76. View in: PubMed

  122. Use of Web-based training for quality improvement between a field immunohistochemistry laboratory in Nigeria and its United States-based partner institution. Ann Diagn Pathol. 2013 Dec; 17(6):526-30. View in: PubMed

  123. Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density. J Natl Cancer Inst. 2013 Sep 18; 105(18):1365-72. View in: PubMed

  124. Accelerated partial-breast irradiation versus whole-breast irradiation for early-stage breast cancer patients undergoing breast conservation, 2003-2010: a report from the national cancer data base. Ann Surg Oncol. 2013 Oct; 20(10):3223-32. View in: PubMed

  125. Axillary surgery among estrogen receptor positive women 70 years of age or older with clinical stage I breast cancer, 2004-2010: a report from the National Cancer Data Base. Ann Surg Oncol. 2013 Oct; 20(10):3259-65. View in: PubMed

  126. Factors associated with compliance to adjuvant hormone therapy in Black and White women with breast cancer. Springerplus. 2013; 2:356. View in: PubMed

  127. Risk factors for pregnancy-associated breast cancer: a report from the Nigerian Breast Cancer Study. Ann Epidemiol. 2013 Sep; 23(9):551-7. View in: PubMed

  128. Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study. Clin Gastroenterol Hepatol. 2013 Dec; 11(12):1601-8.e1-4. View in: PubMed

  129. Incidence rate of breast cancer in young women. JAMA. 2013 Jun 19; 309(23):2433. View in: PubMed

  130. Relationship between household air pollution from biomass smoke exposure, and pulmonary dysfunction, oxidant-antioxidant imbalance and systemic inflammation in rural women and children in Nigeria. Glob J Health Sci. 2013 Mar 18; 5(4):28-38. View in: PubMed

  131. The use of allelic imbalance to ascertain cis-regulation for human UGT2B7 in vivo. Eur J Clin Pharmacol. 2013 Sep; 69(9):1733-5. View in: PubMed

  132. Expression and sub-cellular localization of an epigenetic regulator, co-activator arginine methyltransferase 1 (CARM1), is associated with specific breast cancer subtypes and ethnicity. Mol Cancer. 2013 May 10; 12(1):40. View in: PubMed

  133. Allergy sensitization and asthma among 13-14 year old school children in Nigeria. Afr Health Sci. 2013 Mar; 13(1):144-53. View in: PubMed

  134. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6. View in: PubMed

  135. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet. 2013; 9(3):e1003212. View in: PubMed

  136. Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers. Carcinogenesis. 2013 Jul; 34(7):1520-8. View in: PubMed

  137. A trend analysis of breast cancer incidence rates in the United States from 2000 to 2009 shows a recent increase. Breast Cancer Res Treat. 2013 Apr; 138(2):633-41. View in: PubMed

  138. MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11. Nat Commun. 2013; 4:1393. View in: PubMed

  139. MicroRNA-30c targets cytoskeleton genes involved in breast cancer cell invasion. Breast Cancer Res Treat. 2013 Jan; 137(2):373-82. View in: PubMed

  140. A genome-wide association study of breast cancer in women of African ancestry. Hum Genet. 2013 Jan; 132(1):39-48. View in: PubMed

  141. Microsatellites in the estrogen receptor (ESR1, ESR2) and androgen receptor (AR) genes and breast cancer risk in African American and Nigerian women. PLoS One. 2012; 7(7):e40494. View in: PubMed

  142. Recurrent BRCA1 and BRCA2 mutations in breast cancer patients of African ancestry. Breast Cancer Res Treat. 2012 Jul; 134(2):889-94. View in: PubMed

  143. Power-up: a collaborative after-school program to prevent obesity in African American children. Prog Community Health Partnersh. 2011; 5(4):363-73. View in: PubMed

  144. 2008 US Preventive Services Task Force recommendations and prostate cancer screening rates. JAMA. 2012 Apr 25; 307(16):1692-4. View in: PubMed

  145. Body fat distribution and breast cancer risk: findings from the Nigerian breast cancer study. Cancer Causes Control. 2012 Apr; 23(4):565-74. View in: PubMed

  146. Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis. 2012 Apr; 33(4):835-40. View in: PubMed

  147. A meta-analysis of male breast cancer in Africa. Breast. 2012 Jun; 21(3):237-41. View in: PubMed

  148. Phase II trial of temsirolimus in patients with metastatic breast cancer. Breast Cancer Res Treat. 2012 Nov; 136(2):355-63. View in: PubMed

  149. Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry. Cancer Epidemiol Biomarkers Prev. 2012 Mar; 21(3):552-6. View in: PubMed

  150. Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry. Breast Cancer Res Treat. 2012 Feb; 132(1):341-5. View in: PubMed

  151. Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution. Clin Cancer Res. 2012 Jan 15; 18(2):350-9. View in: PubMed

  152. Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival. Breast Cancer Res Treat. 2012 Jun; 133(3):865-80. View in: PubMed

  153. High prevalence of BRCA1 and BRCA2 mutations in unselected Nigerian breast cancer patients. Int J Cancer. 2012 Sep 01; 131(5):1114-23. View in: PubMed

  154. Novel germline PALB2 truncating mutations in African American breast cancer patients. Cancer. 2012 Mar 01; 118(5):1362-70. View in: PubMed

  155. High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML). Leuk Lymphoma. 2012 Mar; 53(3):445-50. View in: PubMed

  156. Lack of association between common UGT2B nonsynonymous single-nucleotide polymorphisms and breast cancer in populations of African ancestry. Int J Cancer. 2012 Jun 01; 130(11):2740-2. View in: PubMed

  157. Reach-out: a family-based diabetes prevention program for African American youth. J Natl Med Assoc. 2011 Mar; 103(3):269-77. View in: PubMed

  158. c-Myc activates BRCA1 gene expression through distal promoter elements in breast cancer cells. BMC Cancer. 2011 Jun 13; 11:246. View in: PubMed

  159. A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk. Hum Genet. 2011 Dec; 130(6):767-75. View in: PubMed

  160. Population-based patterns and predictors of prostate-specific antigen screening among older men in the United States. J Clin Oncol. 2011 May 01; 29(13):1736-43. View in: PubMed

  161. Germline mutational analysis of the C19orf62 gene in African-American women with breast cancer. Breast Cancer Res Treat. 2011 Jun; 127(3):871-7. View in: PubMed

  162. Protective effect of longstanding lactation and reproductive factors: a case-control study in North Tanzania. Breast Cancer Res Treat. 2012 Aug; 134(3):1349-51. View in: PubMed

  163. SNP discovery, expression and cis-regulatory variation in the UGT2B genes. Pharmacogenomics J. 2012 Aug; 12(4):287-96. View in: PubMed

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